Showing posts with label Vaccine Optimization. Show all posts
Showing posts with label Vaccine Optimization. Show all posts

Tuesday, 30 September 2014

Ways to Optimize Vaccine Allocation During Epidemic



The vaccine optimization, in first place is essential to curb the malady of endemic diseases. The next issue is to ensure the allocation of optimized vaccines before letting pandemic outbreaks to catch up. Taking the case of HINI virus irruption, the onslaught initiated in April 2011, but the vaccines were not available late until the secondary outbreak inflicted humanity by October.


The strategy to cure the speedy transmission

To strategically place the vaccine formulation development in the areas as per geographical demography is the challenge. The vaccination research labs across continents primarily focus upon even and rapid dispersion. As a result, development of deterministic endemic model within disparate age groups is devised. The model is bifurcated in two divisions, adult and children and is subdivided further on the basis of risk levels— high and low.

Methods and Findings

The setting in the model is a replication of a developed country wherein children account for 25% of the total population. For each of these populations, the mortality rate or the hospitalization is minimized. The next step is to formulate an optimal vaccination strategy that gives the best vaccine allocation, given a starting vaccination time and vaccine coverage level. 

The location of the population structure is identified, as it is an important factor in influencing the optimal vaccine distribution. Moreover, the optimal policy is subjected to radical changes.  For example, with 30% vaccine coverage, it is judicious to safeguard the high-transmission groups before this point, but it is ideal to protect the most vulnerable and prone groups afterwards urgently.

Elaborating the scenario for a developed economy, as the vaccine supply escalates it becomes imperative to allocate the resources in the high-transmission group, which counts for children as the target victims. Only after protecting the highly vulnerable groups the chain of transmission can be curtailed from advancing its ensnaring claws further.

Summing up

Choosing the optimal scheme before or early in the epidemic makes a significant difference in minimizing the number of endemic afflictions, and consequently the helps in cutting down over the death toll or mortality rates.

Thursday, 3 July 2014

What are The Myths Associated to Vaccine?



Misunderstandings go hand in hand with vaccines. Such misapprehensions exist because many do not understand the way vaccines function. Every strategic advisory group has strived to spread the correct information about vaccines. The knowledge of vaccines in India is still less. Several vaccine-related myths populate the memory of a large part of Indian population. Let us debunk myths associated to vaccinums. Continue reading...




Myth 1 – Getting an overwhelming dose of vaccines can be harmful for a child’s immune system

The immunisation schedule for many parents is daunting. Parents, however, must realize that every immunization schedule is designed keeping in mind a child’s growth and development. Vaccinums never badly affects a child’s immune system. The bodies of babies are immunologically challenged every second by the dust they breathe, and the food (having traces of bacteria) they eat. Hence, babies have the capacity to react safely to the immunological challenges put up by a vaccine.

Myth 2 – Other children’s vaccinations can support a child’s immune system

Skipping vaccination sessions is never done in a child’s interest. By ignoring vaccine programs, parents put their child’s life in danger. The phenomenon to enjoy the protection got from a group of vaccinated individuals is known as herd immunity. The herd immunity, however, does work when a large number of vaccinated children/people exist. If the number of vaccinated people is low, then herd immunity can’t be enjoyed. The herd immunity for measles will be achieved only when 95 percent of population is vaccinated.

Myth 3 – No vaccinations are required as major illnesses have disappeared

Mankind has possibly controlled major diseases. Still it is not easy to say that the global population does not require any type of vaccines. To date, a few diseases – such as pertussis and measles – have the capacity to infect a large amount of population. In 2003 in the U.S., many children died due to pertussis.

These and many other myths surround vaccinations. Getting vaccinated is important for children as well as adults. The advances in medicine and vaccinology have helped in achieving success with vaccine optimization.

Wednesday, 17 April 2013

Ensuring Global Health through Vaccine Optimization for a Better Tomorrow



Development of vaccine
is a strategic, slow and complex process that can be initiated by reliable and experienced labs. Over a time the system for developing, testing and regulating vaccine optimization has been modified to ensure improved performance. These days testing labs are adopting updated standards and regulatory policies to develop safe vaccines of high quality which are giving good results. The involvements of certain steps in vaccine delivery are significant to reduce the risks and improve the overall results. The process which has been followed to develop vaccines are being tested, and regulated in a very similar manner to other drugs. In general, vaccines are even more thoroughly tested than non-vaccine drugs because the number of human subjects in vaccine clinical trials is usually greater. In addition, post-development monitoring of vaccines is closely examined by the higher departments of disease control.

Safety is also an important phase in different types of the vaccine development process utilized by numerous labs all across the globe. Proven adverse events from the use of licensed vaccines are rare, and vaccines with known safety problems have been removed from the market. Successful vaccinations are highly effective and used globally in order to ensure critical health aspects with the removal of long medication processes. We have been heard that precautions is better than cure, vaccine is supporting this fact on the whole.

Immunization chart is the best and only way that parents can adopt to reduce the chances of skipping any of the vaccine of their child in the initial years of the birth. This chart includes age, vaccination name and how it is given, that facilitates you to track and not to skip any vaccination of your child and brought consistency.

Apart all the benefits of developing a vaccine, it has some major or minor obstacles that can be broadly classified as economic obstacles, technical obstacles and cultural obstacles. Successful vaccines have the scope of introducing and supporting new programs to deliberately providing positive consequences. Vaccines have helped eradicate the worst infectious diseases in the developed world. Research and development must continue the progress of the past and address those diseases that have eluded the development of effective vaccines and the diseases that continue to devastate regions where vaccines have been unavailable. Research is also needed to improve existing vaccines.

There are certain misconceptions related to vaccination, that it should fulfill a net cost-savings is a major obstacle to vaccine development. As a matter of fact costing of vaccination is one of major obstacle in India or outside. To resolve this with consistent approach governments and individuals should be prepared to pay a certain cost to improve health and avoid suffering. Recently studies shows that vaccine development is hampered by the current pricing structure in the U.S., which for some diseases fails to allow adequate compensation for the companies that develop vaccines in the early years following license. Paying prices for vaccines that take into account their health and lifesaving attributes, would encourage more research, more innovation, and better, safer vaccines.

Saturday, 6 April 2013

Prepare Immunization Chart for Children to Bestow Good Health to your Newborn Baby


                       

Good health is the best gift you can give to your new born baby, as we all are aware of the fact that newborn babies are prone to get affected easily by viruses or diseases because of their low immunity level in comparison to adults. Therefore newborn babies need to be cared the most which is feasible when parents are well informed and literate about all the major or minor aspects of child immunization and prepare an easy to remember immunization chart for children after consulting an experienced doctor. Your family doctor could also suggest you the best laboratories in your town from where you can get all the vaccines for your children.

If you are expecting a baby then I recommend you to research as much as you can as it will surely provide information about the recent development in immunization and vaccine schedule for children. Hence your child can enjoy an immunized life. Here are some research based vaccine recommendations that would certainly help you to prepare an immunization chart for children. However the wise way is always to consult your family doctor to take help and make sure you would not skip even a single vaccination of your baby.

At the time of birth, vaccinations that are suggested are Hepatitis B: Hepatitis B vaccine (HBV); recommended to give the first dose at birth within 12 hours, but may be given at any age for those not previously immunized.

The child of age group 1 to 2 months, the recommended vaccine is Hepatitis B: Second dose should be administered 1 to 2 months after the first dose.

The children of 2 months, the suggested vaccines are for DTaP: Diphtheria, tetanus, and acellular pertussis vaccine. Hib: Haemophilus influenzae type b vaccine, IPV: Inactivated poliovirus vaccine, PCV: Pneumococcal conjugate vaccine, Rota: Rotavirus vaccine.

During the age of 4 months, the recommended vaccines are DTaP, Hib, IPV, PCV, and Rota. Once your baby reaches the age of 6 months, the recommended vaccines are DTaP, Hib, PCV and Rota.

With the arrival of new advancements in the health sector, world’s best laboratories are contributing their best possible efforts and funds towards initiating global immunization programs and campaigns in rural areas of developing countries. As the world is witnessing the change in terms of economic and social development, health sector has also shown an outgrowth therefore the development of vaccines has increased rampantly to meet the growing needs of the inhabitants from all across the globe.

According to CNN Health, the most notable change to the vaccination schedule in the 2013 version is that what had been two schedules — for ages 0 to 6 and 7 to 18 — has been consolidated into "one comprehensive list, covering children from birth through age 18". There are some suggestive measures that can be taken up and would definitely help you to be well-informed about the proficient laboratories that are well-known and gained substantial prominence in vaccine optimization for children.